preparation and characterization of electrospinning peg-pla nanofibers for sustained release of tamoxifen

Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems

Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties. However, the low efficiency of the gene delivery by these copolymers is an obstacle to gene therapy. Here, we have investigated nanoparticles formulated using the p...

Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems

Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties. However, the low efficiency of the gene delivery by these copolymers is an obstacle to gene therapy. Here, we have investigated nanoparticles formulated using the p...

Effect of different mass ratio of PLA: PEG segments in PLA-PEG-PLA copolymers on the physicochemical characterization and DNA release profile

Background: Adapting controlled release technologies to the delivery of DNA has the great potential to overcome extracellular barriers that limit gene delivery. This study investigates the effect of different mass ratio of PLA: PEG in the various tri block poly (lactic acid)-poly (ethylene glycol) - Poly (lactic acid) copolymer (PLA-PEG-PLA) on the properties of the resulting nanoparticles. Me...

Preparation and characterization of ZnS:Cu/PVA composite nanofibers via electrospinning

ZnS:Cu/Poly(vinyl alcohol) (PVA) composite nanofibers have been successfully prepared by electrospinning technique. The formation of ZnS: Cu/PVA nanofibers were carried out by reacting H2S with Zn(AC)2:Cu/PVA nanofibers, which were electrospun from the mixture aqueous solution of Zn(Ac)2, Cu(Ac)2 and PVA. Scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray-diffr...

Preparation and Characterization of SnO2 Nanofibers via Electrospinning

Tin oxide (SnO2) nanofibers are successfully prepared by electrospinning homogeneous viscous solutions of tin acetate in polyvinylpyrrolidone (PVP). The electrospinning is carried out by applying a DC voltage to the tip of a syringe and maintaining the tip to collector distance (TCD), i.e. at DC electric field of 1.25 kV∙cm−1. The electrospun nanofibers are calcined between 550 ̊C and 650 ̊C for ...

preparation and characterization of poly(e-caprolactone)–poly(ethylene glycol) – poly(e-caprolactone) nanoparticles for sustained release of tamoxifen